NO. This round is for varmints like foxes, coons etc.
This projectile is ONLY 110 grains. Very light. I highly suggest you use a heavier round like a 168, 175 or 180 grain. This will help for two reasons. One, your projectile will drift less due to the wind at longer ranges. Two, a heavier round equals a larger amount of energy transferred into the animal. This in turn allows for a much better chance of a quick and humane kill as well as helps to reduce possible recovery/time spent tracking the antelope because it ran away wounded. Personally, I shot my first antelope with a 168 grain projectile as it was trotting away at 407 yrds. The antelope ran 4 ft afterwards....straight to the ground.
While the bullet/projectile weight at 110 grains is sufficient for pronghorn, the bullet/projectile construction is not. This bullet is meant to disintegrate with little penetration because varmints are small and light skinned. Pronghorn are big game and presumably you will eat the meat, you don’t want tons of bullet fragments in your meat. Look for copper or bonded bullets, or even hornady interlock bullets. They offer good penetration and expansion.