Wilcox does not state what cartridges the Wilcox RAPTAR S Rangefinder w/Eye Safe IR Laser will work with. I recommend contacting Wilcox for that information.
Applied Ballistics can provide a ballistic curve profile for any type of ammunition, including 22LR. For 22 LR round-nose bullets, I use BCs in the 0.072 to 0.149 range for bullets weights of 26 to 40 grains. When building a new 22LR profile in AB, I start with .10 as my starting BC. If I don't have a chronograph with me, I use the fps stated on the box of ammo. I will zero my rifle at 25 yards. I then shoot out to 100 yards and compare the drop in my scope to the Range Card that Applied Ballistics created. If the Range Card drop aligns my shot out to 100 yards, then I keep the BC at .10. If the Range Card says I need less drop, then I increase the BC from .10 to .12 and reshoot, adjusting until my actual drop is aligned with the Range Card. Once I get my BC adjusted, I will confirm the AB Range Card with shots out to 300 yards (furthest I usually shoot 22LR). I then make any necessary adjustments using Drop Scale Factor.