This Live Free Armory LF19 Chamfered Series Pistol Slide is only compatible with Gen 1-3 Glock 19 model pistols.
No. The Vortex Venom uses a Docter/Noblex optic footprint. You would need a slide that is compatible with Gen 5 Glock 19 model pistols that uses a Docter slide cut. I would recommend the TRYBE Defense Glock 19 Pistol Slide, found by using the link below:
https://www.opticsplanet.com/trybe-defense-glock-19-pistol-slide-version-2.html?_iv_optic-cut=vortex-venom&_iv_model-generation=5
Look for the slide that has RMR cut in the title. This picture is a placeholder for the non cut version of this slide. The slide that is cut for an optic has hole that are tapped already. It is a replacement slide for the Gen 3 Glock 19. You will need the completion parts, a barrel, recoil spring assembly and sights.
This model has the optic cut https://www.opticsplanet.com/live-free-armory-lf19-chamfered-series-pistol-slide-w-rmr-optic-cut-glock-19.html
This is the non optic cut version.
For the optic cut version here is the link https://www.opticsplanet.com/live-free-armory-lf19-chamfered-series-pistol-slide-w-rmr-optic-cut-glock-19.html