Yes, they will work on the Glock Gen5.
Monte @ XS
The XS Sight Systems DXW2 Standard Suppressor Dot Sight set can lower 1/3 co-witness with a Trijicon RMR on an RMR cut slide. These sights are not compatible with MOS model Glocks.
The XS Sight Systems DXW2 Standard Suppressor Dot Sights will allow you to see over your muzzle device as they are designed to be used with suppressors, which are typically longer than a standard muzzle device. Email us at Techsales@opticsplanet.com if you have any further questions.