It will vary by the individual using it, as no two peoples astigmatism is exactly the same.
The lower 1/3 co-witness mount with the standard height AR sights. So you will be able to use Daniel Defense Iron sights while the Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight is mounted to the rifle.
This would be a good option for your firearm, I'd recommend MPN: 2200004 with the low mount for optimal mounting height.
If you add a rail to the top of the ACOG, you could mount this on top, however I would recommend using the RMR instead on top of the ACOG.
This sight is a little large for a pistol, an RMR might be a better fit for your gun, but that said, it would still work for you. You would need the low mount, and you would need a picatinny rail mounted on your Mk 2.
No, the Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight requires a proprietary mount for the Trijicon MRO footprint. Compatible mounts can be found linked below:
https://www.opticsplanet.com/s/trijicon-mro?_iv_categories=red-dot-sight-mounts&_iv_gridSize=240
The Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight does not have a shake awake function.
For your rifle, or any AR15 platform rifle, the absolute or lower 1/3 mounts would be the best options. The absolute mount will co-witness with standard height iron sights on an AR platform rifle, while the lower 1/3 mount would have the iron sights appear in the lower 1/3 of your optics window. Centerline height for absolute is 1.4", centerline height for lower 1/3 is 1.6".
The height you need for the Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight will depend on the magnifier you are using and the height it is sitting at. If you have a magnifier that has spacers to allow for absolute or lower 1/3 co-witness I recommend using the Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight with the absolute co-witness mount or lower 1/3 mount based on the height you want the red dot then adjust the magnifier.
To mount the Trijicon MRO 1x25mm 2 MOA Reticle Red Dot Sight to an AK47 I recommend using the MRO with the low picatinny mount if you have a picatinny rail mount on your rifle.